Crestor (Rosuvastatin) prescription available online

If you are suffering from high cholesterol, Crestor can help. Get a new prescription or refill of Crestor today from a board-certified doctor online.*

Book an appointment

Relieve high cholesterol symptoms

Request Crestor in as little as 15 minutes, with or without insurance*

Stay on top of your cholesterol

*Prescriptions are provided at the doctor’s discretion. Learn more about our controlled substances policy and how you can save up to 80% with our prescription discount card.

About Crestor

Crestor is considered a statin or HMG CoA reductase inhibitor, which functions by reducing the amount of LDL cholesterol that circulates through the bloodstream. Like any statin, this medication can only be used for high LDL cholesterol levels. LDL is sometimes referred to as bad cholesterol and can cause blood vessels to become blocked. This can significantly increase the risk of serious health problems, such as premature coronary heart disease. It is ineffective against other cardiovascular risk factors because it will not help with blood pressure or similar problems.

Some conditions that Crestor is known to treat include high cholesterol. Crestor is available only by prescription. It is available in a generic formulation as well as under different brand names, including rosuvastatin. 

Crestor may be prescribed as a tablet. Patients are advised to take Crestor tablets whole to ensure efficient delivery of the rosuvastatin calcium in the medication. It’s always important to follow the specific instructions on your prescription, as they can vary based on the formulation and dosage that you are prescribed.

If you are prescribed Crestor, be sure to complete the full course of the statins unless your doctor specifically tells you to stop.

If you don’t complete your prescription, the statins may not fully treat your high cholesterol. The cholesterol lowering medicines may be taken for an extended period to help manage cholesterol levels.

Crestor tablets do not only work on LDL (low density lipoprotein) levels in the body. Along with other treatment mechanisms, Crestor tablets can also help to improve high density lipoprotein (HDL cholesterol) and reduce the triglyceride levels in the body.

Crestor uses

There is one FDA-approved use for Crestor, but it may also be used off-label to treat other conditions. Your online medical professional may prescribe it for any of the following common reasons. It’s also possible that your health care provider may prescribe it for other reasons not listed here. If you have questions about why a medication is prescribed, ask your online doctor or pharmacist.

  • High levels of low density lipoprotein

    There are different types of cholesterol in the human body. LDL, or low density lipoprotein, is a type that can have adverse effects on blood vessels and the cardiovascular disease. As the LDL cholesterol builds up in blood vessels, it can cause blockages. This restricts blood flow and can increase the risk factors for certain cardiovascular events. In addition to cardiovascular disease in general, this effect also causes an increased risk for heart attack and stroke.

  • Heterozygous and Homozygous familial hypercholesterolemia

    In certain cases, Crestor may also be used as a treatment for high cholesterol problems that are hereditary. This includes both heterozygous and homozygous types of high cholesterol. In these situations, the medicine may be used for children if they are older than seven or eight years of age, depending on the form of high cholesterol they have.

Crestor side effects

  • The side effects associated with taking Crestor are typically mild. Most Crestor side effects are associated with muscles and the digestive system. Crestor has some common side effects. They may include:

    • Headaches

    • A general weak feeling

    • Muscle aches

    • Nausea

    • Stomach pain

    Sometimes, the muscle aches may feel more severe when you only start out the medication. The muscle pain will usually subside. If you continue to experience muscle pain, tell your doctor about this side-effect. Your doctor or pharmacist may recommend options to help manage muscle aches as a side-effect to Crestor. You should also tell your doctor immediately about sudden unexplained muscle pain.

    Other side effects, which are less common but might be more severe, could include:

    • Liver Disease: It is sometimes possible for the HMG COA Reductase inhibitors to cause problems with liver enzymes. When your liver enzymes are affected while taking Crestor, then you may experience symptoms related to liver disease. This may include stomach pain in the upper abdomen, a poor appetite, and jaundice symptoms. Tiredness and dark urine are also potential symptoms.

    • Allergic Reaction: Some cases of allergic reactions have also been reported among people taking Crestor. If you have an allergic reaction to the medication, then you may experience hives, swelling in certain parts of your face, and breathing problems. Call your doctor immediately if you experience signs of an allergic reaction. You may need to visit a local hospital or facility for emergency medical help.

    You should call your doctor if you notice any of these side effects or if you develop any other new or concerning symptoms. The use of Crestor is only appropriate in children under 12 years of age if they have hereditary conditions that cause high cholesterol levels.

How to take Crestor

Your pharmacist will provide you with instructions on how to take your Crestor prescription.

Be sure to read your prescription label and follow the instructions. Call your doctor or pharmacy if you have any questions.

Crestor can come in different forms and doses, so be sure to follow the specific instructions on your prescription. It is typically prescribed one time every day. Some specific instructions may include taking Crestor at the same time every day. This can help to reduce the risk of a missed dose, which could adversely affect the way that Crestor helps.

It is important to ensure patients taking Crestor understand the important role that diet plays. A proper diet can help to improve the results of the Crestor treatment plan. You should develop a cholesterol-lowering diet plan that reduces your intake of unhealthy fatty substances. This can further help to ensure LDL cholesterol will not block blood flow.

What to avoid while taking Crestor

Crestor has several drug interactions that patients should take into consideration when they treat high cholesterol. Don’t change what you are taking without checking with your doctor or pharmacist. That includes other medications or supplements, as well as over-the-counter drugs. 

When taking Crestor, do not combine it with the following medications:

  • Antivirals for hepatitis C or HIV

  • Blood thinner medications

  • Cancer drugs

  • Colchicine

  • Cyclosporine

You should also avoid medications that use nicotinic acid or niacin as active ingredients. Crestor patients should tell their doctor or pharmacist if they use other cholesterol-lowering medicines. There are specific drug interactions that may occur. Taking Crestor with other statins may increase the risk of muscle pain and other potential side effects.

Ask your doctor or pharmacist if it is acceptable to consume alcohol while taking Crestor.

Some research shows that regular alcohol consumption may impact cholesterol levels. Be careful about alcohol potentially reducing the efficacy of your rosuvastatin calcium while you are being treated for high cholesterol.

Medication alternatives to Crestor

If your healthcare provider prefers to put you on another treatment altogether, they may suggest another statin or a cholesterol-lowering medication in another drug class. Here are some common doctor-recommended alternatives based on your health issue:

  • Primary hypercholesterolemia

    Primary hypercholesterolemia, sometimes also known as familial hypercholesterolemia, is a condition with problems with a specific receptor needing to uptake LDL cholesterol particles. In this case, too much LDL cholesterol remains in the patient's body. A healthcare provider may prefer the use of an alternative drug in the treatment of this particular condition. These drugs may also put the patient at risk of liver disease, stomach pain, and other complications. Talk to your doctor if you are concerned about potential adverse reactions.


    Gemfibrozil (Lopid)

Crestor prescription FAQs

  • How much does Crestor cost?

    The cost of Crestor is not the same for every prescription and can also differ between various pharmacies. Talk to your doctor or pharmacist if you are not sure about the costs that you will need to cover from your side.

  • How can I refill my Crestor prescription?

    If you are taking Crestor, you will usually use the medication for some time. This means you need a repeat script and should refill it once a month at your local pharmacy.

  • Who should not take Crestor?

    Taking Crestor is not advisable for people who have existing problems with their liver. The rosuvastatin calcium in Crestor may cause adverse reactions in the patient's liver. Do not take Crestor with active liver disease, as it may worsen the condition. Avoid taking Crestor if you previously experienced an allergic reaction to rosuvastatin calcium. This medication is also not appropriate for people who are pregnant or breastfeeding. The rosuvastatin calcium in the drug may enter breast milk or affect an unborn baby.

  • What should you avoid when taking Crestor?

    You should avoid the use of excessive alcohol if you are taking Crestor. It is also important to ensure you also tell your doctor about other medications you use. They can determine if there are any potential interactions that may occur.

  • What time of day is best for taking Crestor?

    You will usually not be advised to take Crestor at a specific time of the day. You are free to choose the time that is most appropriate for you, although you should make it a habit to take it at the same time each day.

  • Do I have to take Crestor for the rest of my life?

    It depends on the severity of your bad cholesterol problem and how well you respond to the treatment while taking Crestor. If your condition shows a significant improvement, then the doctor may reduce your dose or take you off Crestor to see how you perform without the use of this medication.

  • What happens if I miss a dose of Crestor?

    A double dose is not something that you should consider in these cases. You may experience more severe muscle problems if you do. Take the dose once you remember, but only if it is not too close to the timing for your next dose.

  • What happens if I take too much Crestor?

    An excessive amount of Crestor can reduce bad cholesterol but also affect other elements of your blood circulatory system. A high Crestor dose can also cause more severe side effects. Make sure you report an overdose to your doctor. Call the medical help center if you have severe symptoms or experience drug hypersensitivity syndrome. They can provide you with emergency medical help to prevent further complications from happening.

3 simple steps to request your Crestor prescription today 

Step 1: Book an appointment

Step 1

Book a Crestor prescription request appointment.

Book a same day appointment from anywhere.

Step 2: Visit with a doctor on your smartphone

Step 2

Talk to your medical provider regarding your Crestor prescription.

Visit with a doctor on your smartphone or computer.

Step 3: pick up at local pharmacy

Step 3

Pick up your Crestor prescription.

We can send prescriptions to any local pharmacy.

Crestor prescription pricing details

How pricing works

To get a new or refill on your Crestor prescription, join our monthly membership and get discounted visits.

Paying with insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price with insurance

Often the same as an office visit. Most patients with in-network insurance pay $30 or less!

  • We accept these insurance plans and many more:

    • Humana
    • Aetna
    • United Healthcare

Paying without insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price without insurance

Initial visits are $129.

Book an appointment

If we're unable to treat you, we'll provide a full refund.


PlushCare is dedicated to providing you with accurate and trustworthy health information.

PlushCare content is reviewed by MDs, PhDs, NPs, nutritionists, and other healthcare professionals. Learn more about our editorial standards and meet the medical team. The PlushCare site or any linked materials are not intended and should not be construed as medical advice, nor is the information a substitute for professional medical expertise or treatment.