Advair Diskus inhaler (Fluticasone-Propionate & Salmeterol) available online

If you are suffering from COPD, bronchitis, asthma, or other breathing difficulties, Advair can help. You can get a new prescription or refill of your Advair inhaler today.*

Book an appointment

Breathe better with Advair

Available as an inhaler

Relief from asthma and chronic respiratory symptoms

*Prescriptions are provided at the doctor’s discretion. Learn more about our controlled substances policy and how you can save up to 80% with our prescription discount card.

About Advair Diskus inhaler

Advair Diskus is an inhaler for treating asthma and other chronic respiratory issues. Advair contain two active drugs: fluticasone propionate, a corticosteroid, and salmeterol, a beta2-adrenergic bronchodilator. While corticosteroids help calm inflamed airways and reduce inflammation, bronchodilators relax the muscles in the lungs and widen the airways.

It's always important to follow the specific instructions on your prescription, as they can vary based on the formulation and dosage prescribed.

If you're prescribed Advair, be sure to complete the entire course of the corticosteroid unless your doctor specifically tells you to stop. Advair may not fully treat your symptoms if you don't complete your prescription.

Advair Diskus inhaler uses

There are several FDA-approved uses for Advair, but your healthcare provider may also prescribe it off-label to treat other medical conditions.

Your PlushCare doctor may prescribe Advair for the following reasons or other reasons not listed here. Ask your online doctor or pharmacist if you have questions about why a medication is prescribed.

  • Asthma

    Advair is FDA-approved to treat asthma in patients aged 4 years and older. Advair treats airway constriction and inflammation to help reduce asthma symptoms.

  • Chronic obstructive pulmonary disease

    Advair is FDA-approved for the maintenance (ongoing) treatment of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. Advair helps improve lung function and reduce COPD symptoms.

Advair Diskus side effects

  • The side effects associated with taking Advair Diskus are typically mild. Individuals taking Advair report a variety of side effects, and side effects may vary from patient to patient.

    The side effects of Advair may include:

    Other side effects, which are less common but might be more severe, could include:

    • Fatigue and weakness

    • Breathing problems that don't improve with Advair

    • Eye problems, such as glaucoma and cataracts

    • Serious allergic reactions

    You should call your doctor if you notice any adverse effects or develop other new or concerning symptoms. The use of Advair in young children under age 12 may lead to an increased risk of ear, nose, and throat infections.

How to take Advair Diskus

Your healthcare professional or pharmacist will be sure to follow instructions on taking your Advair prescription. Be sure to read your prescription label and follow the instructions. Call your doctor or pharmacy if you have any questions.

For asthma, the starting dose of Advair Diskus is one inhalation (puff) in the strength of 100 mcg/50 mcg, 250 mcg/50 mcg, or 500 mcg/50 mcg. The frequency is twice per day, about 12 hours apart.

For COPD, the standard dosage for adults is one puff of 250 mcg/50 mcg twice daily, about 12 hours apart.

What to avoid while taking Advair Diskus

Advair has several drug interactions. Don't change your medications without talking to your healthcare professional or pharmacist. This includes prescription medicine, supplements, and other medications.

Some possible drug interactions with Advair include:

Beta-blockers may also interact with Advair Diskus. These include:

Avoid drinking large amounts of alcohol while taking Advair Diskus. Alcohol may trigger asthma attacks and increase your risk of tachycardia (rapid heartbeat).

Medication alternatives to Advair

If your healthcare provider prefers to put you on another treatment, they may suggest another corticosteroid, a beta2-adrenergic bronchodilator combination, or an inhaler in another drug class. Here are some common doctor-recommended alternatives based on your health issue:

Advair prescription FAQs

  • How much does Advair Diskus cost?

    Depending on your pharmacy, Advair Discus powder costs approximately $169 for a supply of fourteen 100–150 mcg doses. Fortunately, generic brands like Wixela Inhub offer an affordable alternative.

  • How can I refill my Advair Diskus prescription?

    Book a virtual appointment with a board-certified PlushCare doctor to refill your Advair Diskus prescription. After reviewing your symptoms, your doctor can send an electronic prescription to your local pharmacy.

  • Who should not take Advair Diskus?

    Avoid taking Advair if you have a severe allergy to milk proteins. In addition, you shouldn't take similar prescription drugs while taking Advair, as taking more than one long-acting beta antagonist can have severe side effects.

  • What happens if I miss a dose of Advair Diskus?

    If you miss a dose of Advair Diskus, skip the missed dose and take the subsequent amount at the regular time. Avoid taking two doses of Advair Diskus to compensate for a missed dose.

  • What happens if I take too much Advair Diskus?

    If you've taken too much Advair, call your doctor right away. If you have severe symptoms, call 911 or seek immediate medical attention.

  • What should I tell my healthcare provider before using Advair Diskus?

    Tell your doctor about any medications you're currently taking. You should also tell your doctor if you have any medical conditions, including:

    • Heart problems, such as high blood pressure

    • Thyroid problems

    • Liver problems

    • Severe allergy to milk proteins

    • Eye problems

  • How should I use Advair Diskus?

    Use Advair Diskus as your doctor prescribes. Avoid using Advair more often than prescribed to avoid adverse effects. Most adults use one inhalation (puff) of Advair twice daily, about 12 hours apart.

  • What are the possible side effects of Advair Diskus?

    The possible side effects of Advair Diskus include:

    • Muscle cramps and bone pain

    • Weakened immune system

    • Fungal infection in the mouth or throat (thrush)

    • Breathing problems

    • Nausea and vomiting

    • Throat irritation

  • How should I store Advair Diskus?

    Store Advair Diskus at room temperature between 68 °F (20 °C) and 77 °F (25 °C). Store Advair in a dry place away from heat and sunlight.

  • What are the ingredients in Advair Diskus?

    Advair Diskus contains fluticasone propionate, a corticosteroid, and salmeterol, a long-acting bronchodilator. Advair also contains lactose monohydrates (milk proteins).

3 simple steps to request your Advair prescription today 

Step 1

Book an Advair prescription request appointment.

You can book a same-day appointment from anywhere.

Step 2

Talk to your medical provider regarding your Advair prescription.

Visit a doctor on your smartphone or computer.

Step 3

Pick up your Advair prescription.

We can send prescriptions to any local pharmacy.

 Advair Diskus prescription pricing details

How pricing works

To get a new or refill on your Advair prescription, join our monthly membership and get discounted visits.

Paying with insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price with insurance

Often the same as an office visit. Most patients with in-network insurance pay $30 or less!

  • We accept these insurance plans and many more:

    • Humana
    • Aetna
    • Cigna

Paying without insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price without insurance

Initial visits are $129.

If we're unable to treat you, we'll provide a full refund.


PlushCare is dedicated to providing you with accurate and trustworthy health information.

PlushCare content is reviewed by MDs, PhDs, NPs, nutritionists, and other healthcare professionals. Learn more about our editorial standards and meet the medical team. The PlushCare site or any linked materials are not intended and should not be construed as medical advice, nor is the information a substitute for professional medical expertise or treatment.