
Acamprosate (campral) prescription available online
Acamprosate (Campral) helps reduce alcohol cravings for individuals who have already quit drinking. Book an appointment to discuss with a doctor if this medication is right for you.
What is acamprosate used for?
Acamprosate helps curb alcohol cravings and is prescribed to individuals who have already quit drinking.³ It is not used to treat withdrawal symptoms or for those still consuming large amounts of alcohol.¹
Acamprosate is commonly part of medication-assisted treatment (MAT), combining medication with behavioral therapy to support recovery.³
How does Acamprosate work?
Dosage and treatment plan
Acamprosate vs. Naltrexone: Which Is Right for You?
Both medications treat alcohol use disorder but function differently:
- Acamprosate: Targets brain chemistry to reduce cravings and prevent relapse.⁸
- Naltrexone: Blocks the brain's pleasure response to alcohol, reducing heavy drinking.⁸
Unlike acamprosate, naltrexone also treats opioid use disorder and is available in tablet or injection form. However, naltrexone has more side effects, including dizziness and fatigue.⁴
A meta-analysis found that acamprosate is better for maintaining abstinence, while naltrexone is more effective for reducing heavy drinking and cravings.⁵
Your doctor will help determine the best option based on your needs and health history.
FAQs about Acamprosate
How long does acamprosate take to work?
Most people notice symptom improvement within a week.³
Can I drink alcohol while taking acamprosate?
If you relapse, continue taking it and consult your doctor.³
Does stopping acamprosate cause withdrawal symptoms?
Does acamprosate interact with other medications?
There are no known interactions with antidepressants, anxiety medications, or over-the-counter pain relievers. Always consult your doctor.²
Is acamprosate safe for individuals with liver problems?
Yes, it is safe for people with liver conditions.⁹
What if I miss a dose?
Take it as soon as you remember, but do not double up if it’s close to your next dose.³
Can acamprosate affect sleep or mood?
Possible side effects include insomnia, anxiety, or suicidal thoughts. Contact your doctor if you experience these.¹
Is acamprosate safe for long-term use?
More research is needed on using it beyond one year.¹¹
Can acamprosate treat other substance dependencies?
No, the FDA has only approved it for alcohol use disorder.¹
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Acamprosate prescription resources
Sources:
PlushCare is dedicated to providing you with accurate and trustworthy health information.
- MedlinePlus. Acamprosate: Drug Information. Accessed on January 10, 2025, at https://medlineplus.gov/druginfo/meds/a604028.html.
- WebMD. Acamprosate Oral: Uses, Side Effects, Interactions, Warnings & Dosing. Accessed on January 12, 2025, at https://www.webmd.com/drugs/2/drug-91488/acamprosate-oral/details.
- National Alliance on Mental Illness (NAMI). Acamprosate. Accessed on January 14, 2025, at https://www.nami.org/About-Mental-Illness/Treatments/Mental-Health-Medications/Types-of-Medication/Acamprosate/.
- Drugs.com. Acamprosate vs. Naltrexone: How Do They Compare? Accessed on January 10, 2025, at https://www.drugs.com/medical-answers/acamprosate-naltrexone-compare-3571175/.
- Maisel, N. C., Blodgett, J. C., Wilbourne, P. L., Humphreys, K., & Finney, J. W. Meta-analysis of Naltrexone and Acamprosate for Treating Alcohol Use Disorders. Accessed on January 12, 2025, at https://doi.org/10.1111/j.1360-0443.2012.04054.x.
- Mason, B., & Heyser, C. Acamprosate: A Prototypic Neuromodulator in the Treatment of Alcohol Dependence. Accessed on January 14, 2025, at https://doi.org/10.2174/187152710790966641.
- Office of Addiction Services and Supports. Medications for the Treatment of Alcohol Use Disorder. Accessed on January 10, 2025, at https://oasas.ny.gov/providers/medications-treatment-alcohol-use-disorder.
- American Family Physician. Naltrexone for Alcoholism. Accessed on January 12, 2025, at https://www.aafp.org/pubs/afp/issues/2000/0315/p1891.html.
- PubMed. Acamprosate. Accessed on January 14, 2025, at https://www.ncbi.nlm.nih.gov/books/NBK548677/.
- The Recovery Village. Treating Alcoholism with Campral (Acamprosate). Accessed on January 10, 2025, at https://www.therecoveryvillage.com/treatment-program/addiction-medications/acamprosate/#.
- Canadian Agency for Drugs and Technologies in Health. Long-term Use of Acamprosate Calcium for Alcoholism: A Review of the Clinical Effectiveness, Safety, and Guidelines. Accessed on January 12, 2025, at https://www.ncbi.nlm.nih.gov/books/NBK304665/.
PlushCare content is reviewed by MDs, PhDs, NPs, nutritionists, and other healthcare professionals. Learn more about our editorial standards and meet the medical team. The PlushCare site or any linked materials are not intended and should not be construed as medical advice, nor is the information a substitute for professional medical expertise or treatment.