As a triple therapy inhaler, Breztri combines three different medications with their own mechanisms of action to manage COPD symptoms.1, 2, 3 These are:
- Budesonide, an inhaled corticosteroid (ICS), which decreases inflammation in the lungs
- Glycopyrrolate, an anticholinergic, which relaxes and widens airway muscles by blocking a neurotransmitter called acetylcholine, which is responsible for muscle contraction
- Formoterol fumarate, a long-acting beta2-adrenergic agonist (LABA), which also relaxes the airways by activating smooth muscle cells
Breztri Aerosphere begins working within about 5 minutes of taking it.1